Title:
Investigation of Antifugal Activity from Scenedesmus sp. and Chlamydomonas sp. Crude Extracts
Author(s):
Dejtisakdi, W., Maneeruttanarungroj, C.
Document(s):
Paper
Poster
Abstract:
Scenedesmus sp. and Chlamydomonas sp. are green microalgae used for various biotechnology applications such as an alternative biofuel, antioxidant, human supplement, aquaculture feed etc. In a decade, finding a new antibiotic resource from a novel organism is significant for pharmaceutical research. Microalgae is a promising candidate since they consist of high-value biocompounds such as ß-carotene, astaxanthin, flavonoids, polysaccharide. In this study, we aimed to preliminarily investigate antifungal activities of Scenedesmus and Chlamydomonas crude extracts against to Candida albicans, a fungal pathogen. We prepared both of intracellular and extracellular (culture media) crude extracts by using ethanol and methanol as a solvent and then tested C albicans inhibition performed by agar-well diffusion assay. From the preliminary results, we found that 50 mg/mL of Scenedesmus and Chlamydomonas ethanolic crude extracts from intracellular and extracellular could inhibit C. albicans. This preliminary finding could be a platform for a further study in some bio-based organic compounds that is significant for pharmaceutical application.
Keywords:
microalgae, Chlamydomonas, crude extracts, Scenedesmus, antifungal capacity, agar-well diffusion
Topic:
Biomass Conversion to Bio-Based Products and Chemicals
Subtopic:
Processes for bio-based chemicals and materials
Event:
30th European Biomass Conference and Exhibition
Session:
6BV.2.1
Pages:
1088 - 1091
ISBN:
978-88-89407-22-6
Paper DOI:
10.5071/30thEUBCE2022-6BV.2.1
Price:
FREE
