Paper details

Title:

Investigation of Antifugal Activity from Scenedesmus sp. and Chlamydomonas sp. Crude Extracts

Author(s):

Dejtisakdi, W., Maneeruttanarungroj, C.

Document(s):

Abstract:

Scenedesmus sp. and Chlamydomonas sp. are green microalgae used for various biotechnology applications such as an alternative biofuel, antioxidant, human supplement, aquaculture feed etc. In a decade, finding a new antibiotic resource from a novel organism is significant for pharmaceutical research. Microalgae is a promising candidate since they consist of high-value biocompounds such as ß-carotene, astaxanthin, flavonoids, polysaccharide. In this study, we aimed to preliminarily investigate antifungal activities of Scenedesmus and Chlamydomonas crude extracts against to Candida albicans, a fungal pathogen. We prepared both of intracellular and extracellular (culture media) crude extracts by using ethanol and methanol as a solvent and then tested C albicans inhibition performed by agar-well diffusion assay. From the preliminary results, we found that 50 mg/mL of Scenedesmus and Chlamydomonas ethanolic crude extracts from intracellular and extracellular could inhibit C. albicans. This preliminary finding could be a platform for a further study in some bio-based organic compounds that is significant for pharmaceutical application.

Keywords:

microalgae, Chlamydomonas, crude extracts, Scenedesmus, antifungal capacity, agar-well diffusion

Topic:

Biomass Conversion to Bio-Based Products and Chemicals

Subtopic:

Processes for bio-based chemicals and materials

Event:

30th European Biomass Conference and Exhibition

Session:

6BV.2.1

Pages:

1088 - 1091

ISBN:

978-88-89407-22-6

Paper DOI:

10.5071/30thEUBCE2022-6BV.2.1

Price:

FREE